Lipoprotein(a), or Lp(a), is a type of LDL particle with an additional protein called apolipoprotein(a) attached to it. Dr. Tsimikas at UC San Diego defines Lp(a) as "2 major proteins stuck together like conjoined twins, apolipoprotein(a) and apolipoprotein B-100."
Your Lp(a) level is primarily set by your genes and is mostly stable over time. Elevated Lp(a) is an independent risk factor for cardiovascular disease, including heart attacks and strokes. About 20% of the population has elevated Lp(a).
Less than 1% of people have tested their Lp(a), but testing rates are increasing. The American College of Cardiology recommends that everyone have their Lp(a) tested at least once in their lifetime (in their 2026 guidelines). Lp(a) levels above 50 mg/dL (or 125 nmol/L) are considered elevated.
Empirical Health memberships includes Lp(a) among 100+ biomarkers for $190.
Lp(a) is a genetic risk factor for heart disease that most people have never tested. Our comprehensive panel includes Lp(a) along with 100+ other cardiovascular, metabolic, and inflammatory markers.
My cholesterol has been high for several years. Empirical Health has helped me understand what this means for my health and how to improve it.
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Test your Lp(a) and 100+ other biomarkers today.
