Macrocyclic peptides: a new "Goldilocks" drug class?
Merck ran more than a dozen screens for a small molecule that could block PCSK9 and found nothing. The drug that finally worked is a ring-shaped peptide, and it took 13 years.
• Brandon Ballinger
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57% of US adults recommended a statin under new guidelines
• Brandon Ballinger
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How much does Lipfendra cost?
• Brandon Ballinger
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PCSK9 inhibitors vs statins
• Brandon Ballinger
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FDA committee votes 8-6 to make BPC-157 legal. What the FDA briefing report said about the evidence.
• Brandon Ballinger
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Why non-invasive glucose monitoring is hard
• Brandon Ballinger
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Coffee brewing method determines its effect on cholesterol
• Brandon Ballinger
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Lipfendra vs Repatha
• Brandon Ballinger
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Lipfendra (enlicitide), the first oral PCSK9 inhibitor, lowers LDL by 60%
• Brandon Ballinger
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Red yeast rice is essentially unregulated lovastatin
• Brandon Ballinger
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Medicare now covers GLP-1s for weight loss. Roughly 4 million qualify.
• Brandon Ballinger
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How to enroll in the Medicare GLP-1 Bridge
• Brandon Ballinger
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Medicare GLP-1 Bridge prior authorization form pdf filler
• Brandon Ballinger
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LLM-style scaling laws hold for sensor data
• Brandon Ballinger
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Wearable foundation models: a brief history
• Brandon Ballinger
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High Lp(a) is not a death sentence
• Brandon Ballinger
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How to refer Medicare patients to the ACCESS cardiovascular model
• Brandon Ballinger
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Medicare coverage for cardiovascular health: the complete guide
• Brandon Ballinger
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PCSK9 inhibitors lower LDL cholesterol by about 60%
• Brandon Ballinger
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Vitamin D regulates >5% of the human genome
• Brandon Ballinger
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Younger generations are aging faster biologically, raising early cancer risks
• Brandon Ballinger
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Blood tests that predict heart attack risk
• Brandon Ballinger
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Do modern LDL formulas replace ApoB?
• Brandon Ballinger
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How to lower inflammation through diet and medication
• Brandon Ballinger
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Statins lower inflammation by 37%
• Brandon Ballinger
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CAC score was zero, but plaque doubled.
• Brandon Ballinger
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Insurance coverage of PCSK9 inhibitors
• Brandon Ballinger
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Nutrition is multidimensional
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The biomarkers to watch when you're on a GLP-1
• Brandon Ballinger
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Dietary cholesterol has a weak effect on blood cholesterol
• Brandon Ballinger
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Eggs are now officially healthy
• Brandon Ballinger
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To lower blood pressure, focus on sodium and potassium
• Brandon Ballinger
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Blood cholesterol is driven by saturated fat and fiber
• Brandon Ballinger
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Medicare covers GLP-1s for $50/month starting July 2026
• Brandon Ballinger
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How to track saturated fat and fiber with an app
• Brandon Ballinger
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Objective metrics that change the most as we age
• Brandon Ballinger
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Retatrutide's phase 3 results: 30% weight loss in 2 years
• Brandon Ballinger
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99% of heart attacks are preceeded by these risk factors
• Brandon Ballinger
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Vitamin D2 vs D3: why the form on the bottle matters
• Brandon Ballinger
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Vitamin D acts more like a hormone than a vitamin
• Brandon Ballinger
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How to improve your VO2Max: an evidence-based guide
• Brandon Ballinger
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How to Get Function Health at a lower cost
• Brandon Ballinger
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Sleep polysomnography predicts 130 health conditions, including cardiovascular disease
• Brandon Ballinger
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The effect of sleep on blood biomarkers
• Brandon Ballinger
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Every statin ranked by effect size
• Brandon Ballinger
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The Fick equation and your heart
• Brandon Ballinger
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A Cal AI alternative for iPhone and Android
• Brandon Ballinger
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Medications can now lower cholesterol (ApoB) by 80%
• Brandon Ballinger
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Does Medicare cover Lp(a) testing?
• Brandon Ballinger
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Four Lp(a)-lowering drugs in trials reduce levels by up to 94%.
• Brandon Ballinger
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Blood pressure may swing 20+ mmHg in a single day
• Brandon Ballinger
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How different wearables measure HRV: SDNN vs RMSSD
• Brandon Ballinger
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Every formula to measure HRV
• Brandon Ballinger
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Lp(a) testing is up 22x in the last decade. It's now recommended for everyone.
• Brandon Ballinger
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How to find potassium-rich foods for blood pressure
• Brandon Ballinger
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Partnering with Beacon Health to help Medicare patients with heart disease
• Brandon Ballinger
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What cardiovascular medications does Medicare cover?
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Normal cholesterol levels (2026 guidelines)
• Brandon Ballinger
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2026 cholesterol guidelines recommend earlier treatment
• Brandon Ballinger
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Autopilots vs. copilots in vertical AI
• Brandon Ballinger
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Blood tests for heart health
• Brandon Ballinger
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Three main saturated fats raise your cholesterol
• Brandon Ballinger
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Why more young adults are dying of heart attacks
• Brandon Ballinger
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Empirical Health for Web: Now Available on Desktop
• Wyatt Chang
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The government wants AI doctors
• Brandon Ballinger
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Bryan Johnson's Immortals program costs $1m. How to DIY 90% of the value for <1% of the price.
• Brandon Ballinger
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Do rich people live longer?
• Brandon Ballinger
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Men's heart risk rises by age 35, 7 years earlier than women
• Brandon Ballinger
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Vitamin D cuts heart attack risk by 52%. Why?
• Brandon Ballinger
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Direct-to-consumer advanced lipid panel with ApoB, Lp(a), and hs-CRP
• Brandon Ballinger
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AI beyond LLMs: a wearable foundation model based on JEPA.
• Brandon Ballinger
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Instead of Giving Stuff, Give Years
• Brandon Ballinger
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The best biomarkers for heart health
• Brandon Ballinger
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How fiber reduces overall mortality by 23%
• Brandon Ballinger
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Peter Attia on 60 Minutes: Medicine 3.0 and the marginal decade
• Brandon Ballinger
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The four horsemen from Peter Attia's Outlive
• Brandon Ballinger
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How to use AI to calculate nutrition facts
• Brandon Ballinger
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Apple Watch hypertension alerts explained
• Brandon Ballinger
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ApoB is not usually covered by Medicare or insurance, but can be cheap.
• Brandon Ballinger
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The biomarkers recommended by Peter Attia in Outlive
• Brandon Ballinger
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Inflammation now predicts heart disease better than LDL
• Brandon Ballinger
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Simulating Reductions in Lifetime Heart Attack Risk
• Brandon Ballinger
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How Apple Watch's new blood pressure monitor works
• Brandon Ballinger
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Why choose Empirical for 100+ biomarkers
• Brandon Ballinger
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Why ApoB is more accurate than LDL cholesterol
• Brandon Ballinger
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How to Get a Sleep Score on Your Apple Watch
• Brandon Ballinger
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The effect of noise on sleep
• Brandon Ballinger
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ApoB vs Lp(a) blood tests for heart health
• Brandon Ballinger
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Data-driven nutrition: how to go beyond generic diet advice
• Wyatt Chang and Brandon Ballinger
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How to lower your ApoB naturally and with medication
• Brandon Ballinger
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How to Lower Your Cholesterol in 7 Days
• Raquel Rodriguez Martinez, MD, MPP
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Function Health alternative in NY & NJ
• Brandon Ballinger
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Function Health Alternatives
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Don't die of heart disease
• Brandon Ballinger
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Lp(a): the strongest hereditary risk factor for heart disease
• Brandon Ballinger
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Apple Watch's calorie counts can be accurate within 18-40%—if you follow these steps.
• Brandon Ballinger
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Cutting ApoB by 10 mg/dL drops heart disease risk by 9%
• Harish Kilaru
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Apple Watch can't predict a heart attack—these blood tests can
• Brandon Ballinger
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How to calculate your heart attack risk with <$200 of blood tests
• Brandon Ballinger
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Am I Healthy? How to design a comprehensive health score
• Raquel Rodriguez Martinez, MD, MPP
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Apple Watch's heart rate monitor is accurate to 5bpm 89-98% of the time
• Brandon Ballinger
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Apple Watch uses three different algorithms for heart rate
• Brandon Ballinger
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Empirical Health Radar: One number, infinite insights.
• Raquel Rodriguez Martinez, MD, MPP and Harish Kilaru
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Your guide to Apple Watch's heart rate monitor
• Brandon Ballinger
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Empirical Health launches today on Android, WearOS, and Fitbit
• Wyatt Chang and Brandon Ballinger
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Which health metrics are available on Samsung, Pixel, Apple Watch, and Fitbit?
• Brandon Ballinger
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How to Do a "Poor Man's Tilt Table Test" on Your Apple Watch
• James Russo
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How Apple Watch's VO2Max algorithm works: physiological ODEs and deep neural networks.
• Brandon Ballinger
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Breathing Disturbances on Apple Watch: What should I do if I get a “possible sleep apnea” alert from my Apple Watch?
• Raquel Rodriguez Martinez, MD, MPP
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How Apple Watch estimates VO2Max to 1.2 ml/kg/min without a treadmill test
• Brandon Ballinger
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The average Apple Watch user gets 49 minutes of deep sleep per night
• Brandon Ballinger
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How to track your mental health with PHQ-9 and GAD-7
• James Russo and Raquel Rodriguez Martinez, MD, MPP
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How Apple Watch detects 89% of severe sleep apnea
• Brandon Ballinger
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Summarize all your Apple Watch vitals into a health report
• Wyatt Chang
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Empirical 2.0: your AI healthcare assistant
• Brandon Ballinger and Raquel Rodriguez Martinez, MD, MPP
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Cardiovascular metrics predict sleep apnea risk
• Brandon Ballinger
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How to correlate your Apple Watch health metrics with symptoms
• Brandon Ballinger
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How to do the CHOP protocol for POTS on your Apple Watch
• Brandon Ballinger
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Empirical Health is launching to 47 million midwesterners
• Brandon Ballinger
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Can my Apple Watch tell me if I have afib?
• Raquel Rodriguez Martinez, MD, MPP
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The CHOP protocol and the science behind it
• Raquel Rodriguez Martinez, MD, MPP
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The best Apple Watch for heart monitoring (2026)
• Brandon Ballinger
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The connection between long COVID and POTS
• Raquel Rodriguez Martinez, MD, MPP
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What are some of the most common POTS triggers?
• Raquel Rodriguez Martinez, MD, MPP
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Do I need a tilt table test to confirm a POTS diagnosis?
• Raquel Rodriguez Martinez, MD, MPP
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Is the Apple Watch's oxygen sensor accurate?
• Brandon Ballinger
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Sleep apnea and the link to cardiovascular health: what you need to know
• Raquel Rodriguez Martinez, MD, MPP
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How far is 10,000 steps?
• Raquel Rodriguez Martinez, MD, MPP
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My Apple Watch says I have low blood oxygen while sleeping.
• Raquel Rodriguez Martinez, MD, MPP
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What are the steps to get a POTS diagnosis?
• Raquel Rodriguez Martinez, MD, MPP
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Why is it so hard to find a primary care doctor near me?
• Raquel Rodriguez Martinez, MD, MPP
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Empirical Health: proactive primary care that scales
• Brandon Ballinger
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What is HRV and what does it have to do with health?
• Raquel Rodriguez Martinez, MD, MPP
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How to show sleep stages on your Apple Watch face
• Brandon Ballinger
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Want better sleep quality? The top 3 factors, according to Apple Watch data
• Brandon Ballinger
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Is my data normal? Introducing Empirical Checkups
• Brandon Ballinger
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Empirical Sleep for watchOS 9
• Brandon Ballinger
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Apple Watch's new temperature sensor
• Brandon Ballinger
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Empirical Sleep for Apple Watch
• Brandon Ballinger