Triglycerides/HDL Ratio

Normal range: 0 – 2 (lower is better)

The TG/HDL ratio is a practical marker of insulin resistance and small, dense LDL particle predominance. Values above 2.0 suggest increased metabolic and cardiovascular risk. It is one of the most actionable lipid ratios because both components respond dramatically to lifestyle changes. Some researchers consider it a better proxy for insulin resistance than fasting glucose.

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What can cause high TG/HDL?

A normal TG/HDL is 0 – 2. Lower is better.

A high TG/HDL ratio is the hallmark of insulin resistance and metabolic syndrome. Excess sugar, refined carbs, and alcohol raise triglycerides while inactivity and obesity lower HDL. This ratio is highly responsive to lifestyle changes: cutting sugar, reducing alcohol, exercising regularly, and losing excess weight can improve it significantly within weeks.

Because both sides of the ratio respond to the same interventions, improvements can be dramatic. A person who starts exercising and cuts sugar may see their triglycerides drop and HDL rise simultaneously, producing a much larger ratio improvement than either change alone.

Biomarkers related to TG/HDL

TG/HDL is most highly correlated with Estimated VLDL and Triglycerides. Here are the top biomarkers correlated with TG/HDL, based on 500,000 tests done by Empirical Health.

The percentage shows how strongly two biomarkers move together. A higher number means the relationship is stronger. Green = rises and falls together. Orange = one rises as the other falls.

TG/HDL test cost

You can test your TG/HDL for $190 as part of Empirical's comprehensive health panel, which includes 100 biomarkers.

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Where to test TG/HDL

You can measure your TG/HDL for at 2,200+ testing locations across the US. Click below and enter your zip code to browse locations near you.

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